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The sub-2 hour marathon recorded for the first time in 2026 was, not that long ago, said to be unachievable by some eminent scientists. This incredible achievement shows how our understanding of the science of exercise is improving rapidly. Whilst there is arguably greater scope for ‘science’ to impact performance in endurance events like marathons, should we expect a sub 2 minute 30 seconds (Epsom) Derby any time soon?